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INDONESIA
Berkala Ilmu Kesehatan Kulit dan Kelamin
Published by Universitas Airlangga
ISSN : 19784279     EISSN : 25494082     DOI : 10.20473
Core Subject : Health, Science,
Immunology & microbiology Public Health
Arjuna Subject : -
Articles 12 Documents
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Search results for , issue "Vol. 34 No. 3 (2022): DECEMBER" : 12 Documents clear
The Role of Topical Treatment on Vaginal Tightening Made Putri Hendaria
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 3 (2022): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.3.2022.203-209

Abstract

Background: Physiological changes in a woman's life, such as labor, weight fluctuations, hormonal changes, aging, and menopause, cause changes in both appearance and function of the vagina. As estrogen deficiency continues, changes occur in the form of atrophy and dystrophy in the vaginal mucosa, vulva, and other structures in the urogenital tract which are called symptoms of vulvovaginal atrophy. It affects women's quality of life, self-confidence, and sexuality. As alternative modality for noninvasive therapy, topical therapy in vaginal rejuvenation is becoming available in the care of outpatients. This makes it increasingly important for dermatologists to be well-informed about these treatment options. Purpose: This review aims to assess the role of topical therapy in vaginal rejuvenation, especially in vulvovaginal atrophy cases. Literature Review: Vulvovaginal atrophy has a negative effect on interpersonal relationships, quality of life, daily activities, and sexual function. Topical hormone replacement therapy includes all preparations such as estradiol, estradiol valerate, or conjugated estrogen. considered in cases with vulvovaginal atrophy accompanied by atrophy of the urogenital system as well as the accompanying complaints because this therapy is intended to prevent systemic complications. The topical use of hyaluronic acid, lubricants, moisturizers, and herbs is a therapeutic choice in vulvovaginal atrophy patients contraindicated with estrogen therapy or in patients who do indeed choose nonhormonal therapy. Conclusion: Topical therapy of hormonal and non-hormonal rejuvenation in various studies has shown improvement in symptoms of vaginal dryness, vaginal itching, dyspareunia, cell maturity, and changes in vaginal pH toward acidity.
Excellent Response of Infantile Hemangioma with Oral Propranolol: A Case Report Armyta Denissafitri; Riezky Januar Pramitha; Iskandar Zulkarnain; Sawitri Sawitri
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 3 (2022): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.3.2022.217-222

Abstract

Background: Infantile hemangioma (IH) is the most common benign tumor in infancy. Most IHs resolve spontaneously and do not require treatment. Therapeutic intervention is necessary for life-threatening IH, tumors posing functional risks, ulceration, and severe anatomic distortion, especially on the face. Beta-blockers, most specifically propranolol, have been shown to induce involution of IH, which should be administered as early as possible to avoid potential complications. Purpose: To report a case of IH with visual impairment treated successfully using oral propranolol. Case: A 4-month-old girl weighing, 6.3 kg, with redness plaques on the right face since 3 weeks after birth. The lesions rapidly increased in size within 2 months, and the lesions on her right eyelid made it difficult to open her right eye. Dermatological examination showed erythematous plaques, compressible and varying in size and ptosis. The patient was diagnosed with periocular infantile hemangioma and was given oral propranolol therapy with an initiated dose 3x1 mg. The dose was increased gradually. The lesions were significantly decreased and she could open her right eye normally after 5 months of propranolol therapy. Discussion: Some cases of IH require early treatment. Early treatment is indicated for IH causing functional impairment. The use of propranolol in the management of IH is very effective in the reduction of the lesions and Has minimal side effects. Conclusion: Early diagnosis and intervention with propranolol for IH play an important role in determining the optimal outcomes.
Borderline Lepromatous Leprosy with Severe Erythema Nodosum Leprosum: A Case Report Nevristia Pratama; Luh Made Mas Rusyati; Prima Sanjiwani Saraswati Sudarsa; IGAA Dwi Karmila; NLP Ratih Vibriyanti Karna
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 3 (2022): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.3.2022.210-216

Abstract

Background: Leprosy is a chronic granulomatous infectious disease caused by Mycobacterium leprae (M. leprae) that primarily infects Schwann cells in the peripheral nerves, leading to nerve damage and the development of disabilities. In 2018, Indonesia was the third country with the most leprosy cases in the world. Erythema nodosum leprosum (ENL), also known as type II leprosy reaction, is a severe immune-mediated complication of multibacillary leprosy. Purpose: To report a case of borderline lepromatous leprosy with severe ENL. Case: A 49-year-old Balinese man presented with multiple tender erythematous skin nodules all over his body, fever, arthralgia, bilateral cervical lymphadenopathy, and sensory loss for the past week. The acid-fast bacilli bacteriological examination showed a positive result. The patient was diagnosed with borderline lepromatous (BL) leprosy with severe ENL and was treated with multibacillary multidrug therapy (MB MDT), methylprednisolone, and other symptomatic medications. After 1 month of treatment, there was an improvement in skin lesions. The MB-MDT treatment was continued and methylprednisolone was planned to be tapered down gradually. Discussion: Approximately 20-50% of all leprosy patients show leprosy reactions in the course of the disease. The goals of treatment for severe ENL are to control inflammation, reduce pain, treat neuritis to prevent nerve dysfunction and contractures, and prevent recurring ENL. The prognosis of leprosy with ENL reactions depends on the severity of the occurring leprosy reaction; early diagnosis and prompt treatment; and patient compliance with treatment. Conclusion: Early diagnosis and treatment are essential to avoid deformities in leprosy patients.
Comparison of Psoriasis Area and Severity Index (PASI) Scores in Patients Treated with Oral Methotrexate and A Combination of Oral Methotrexate and Narrow Band-Ultraviolet B (NB-UVB) Phototherapy Ervina Rosmarwati; Nurrachmat Mulianto; Bobby Febrianto; Dita Eka Novriana; Siti Efrida Fiqnasyani
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 3 (2022): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.3.2022.169-173

Abstract

Background: Psoriasis Vulgaris is an autoimmune disease characterized by chronic skin inflammation and epidermal hyperplasia. Psoriasis Area Severity Index (PASI) score is one of the assessments to measure the psoriasis severity. Oral methotrexate is one of the effective therapies for psoriasis patients. Narrow Band-Ultraviolet B (NB-UVB) phototherapy is an adjunctive psoriasis therapy given concurrently with oral methotrexate. Purpose: Determine the difference in Psoriasis Area Severity Index (PASI) scores between Psoriasis Vulgaris patients treated with oral methotrexate and a combination of oral methotrexate and NB-UVB phototherapy. Methods: This observational analytic study was conducted at the Dermatology and Venereology Clinic, Dr. Moewardi General Hospital Surakarta. The patients received oral methotrexate and a combination of oral methotrexate and and Narrow Band-Ultraviolet B (NB-UVB) phototherapy. A retrospective study of medical records was conducted to determine the patient's PASI score before the therapies and 3 months after. All data were analyzed with the Shapiro Wilk normality test and the independent T-test. A p-value was <0.05, and it was considered significant. Result: The mean of decreased PASI scores in the oral methotrexate group was (6.00 +2.47) and (6.08 +2.17) in the combination therapy group. Based on the statistical test results from the 24 subjects, it was found that the PASI score decreased (p=0.931). Conclusion: There was no significant difference in the decrease in PASI between the oral methotrexate group and the combination therapy group. The mean reduction of PASI scores was more significant in the combination therapy than in the methotrexate group
Pediatric Viral and Bacterial Skin Infection Profile Rully Setia Agus Dimawan; Flora Ramona Sigit Prakoeswa; Ratih Pramuningtyas
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 3 (2022): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.3.2022.184-188

Abstract

Background: Viral and bacterial skin infection is a common condition amongst children. In developing countries, it is a complex major health problem. However, epidemiological study on viral and bacterial skin infection in the pediatric population is still lacking, especially in Indonesia. Purpose: This study aimed to evaluate bacterial and viral skin infection amongst children and its association with age and sex. Methods: This study used a cross-sectional design with a retrospective approach. We retrieved medical records of pediatric patients admitted to Dr. Harjono S Ponorogo General Public Hospital between 2016 and 2020. Result:  Of the 1,427 collected medical records, we found that the viral infection prevalence was 4.9% (n=70) and 7.5% (n= 107) for bacterial skin infection. Viral infection was most observed amongst subjects in the >12-year age group and 2–12-year for bacterial infection. Infection was more commonly observed amongst boys. Conclusion: The skin infection prevalence in Dr. Harjono S. Ponorogo General Hospital is lower compared to other studies. Skin infection of viral origin was most reported in children aged >12 years and bacterial infection in children aged 2–12. Both skin infections were more commonly observed in boys than girls.
Comparison of Antifungal Susceptibility Basil Leaves Extract (Ocimum sanctum Linn.), Eugenol, and Nystatin against Isolates of Candida spp. as Important Agent causing Oral Candidiasis in HIV/AIDS Patient Emma Hidayati Sasmito; Afif Nurul Hidayati; Rahmadewi; Sawitri; Budi Utomo; Sudjarwo; Pepy Dwi Endraswari; Diah Mira Indaramaya; Dwi Murtiastutik
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 3 (2022): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.3.2022.162-168

Abstract

Background: Oral candidiasis is an infection caused by Candida sp. in areas of the oral mucosa that are often found in HIV/AIDS patients. Increased antifungal resistance, it was important to find new antifungal candidates, especially from natural ingredients, basil leaf extract (Ocimum sanctum Linn.) which had major compound of eugenol that had an antifungal effect in inhibiting of Candida sp. Purpose: To evaluate the comparison of the antifungal susceptibility of nystatin, basil leaf extract (Ocimum sanctum Linn.) and eugenol against isolates of Candida sp. Methods: This study examined the comparison of the antifungal susceptibility of nystatin 100 IU, basil leaf extract (Ocimum sanctum Linn.) with doses equivalent to 800 µg/mL and 400 µg/mL eugenol, and eugenol 800 µg/mL and 400 µg/mL against 40 stored isolates of Candida sp. from the oral cavity of HIV/AIDS patient which was reactivated. Result: The mean inhibition zone of nystatin for all isolates was 22.98 mm, while the mean inhibition zone of eugenol with doses of 800 µg/mL and 400 µg/mL were 17.07 mm and 15.89 mm, and the mean inhibition zone of basil leaf extract (Ocimum sanctum Linn.) with doses equivalent to 800 µg/mL and 400 µg/mL eugenol are 14.87 mm and 14.01 mm. The inhibition zone of basil leaf extract (Ocimum sanctum Linn.) and eugenol was significantly lower than nystatin (p = 0.001; p < 0.05). Conclusion: The zone of inhibition of nystatin was significantly higher compared to basil leaf extract (Ocimum sanctum Linn.) and eugenol against Candida albicans and Candida non-albicans isolates.
Clinical Profile and Treatment of Acne Vulgaris Patients M. Yulianto Listiawan; Farah Meriana Fajrin; Rahmadewi Rahmadewi; Afif Hidayati; Sawitri Sawitri; Diah Mira Indramaya; Rebekah Juniati Setiabudi; Maya Wardiana
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 3 (2022): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.3.2022.156-161

Abstract

Background: Acne vulgaris (AV) is not a deadly condition may affect one’s quality of life. Treatment of AV includes topical and oral, depending on the severity. Antibiotics as oral treatment should not be given alone because it can precipitate resistance. Purpose: To describe the clinical characteristics of AV in a tertiary hospital in Indonesia and evaluate the treatment given. Methods: This is a descriptive, retrospective study with a cross-sectional design. The study subject was classified based on severity according to Plewig and Kligman’s acne grading. Further evaluation was made according to the type of lesion, the risk factortopical and oral treatment in subjects with grades 2, 3, and 4. This research was conducted at the Cosmetic Medic Division, Dermatology and Venereology Outpatient Clinic at Dr. Soetomo General Academic Hospital Surabaya based on medical records from the period of 2017 to 2019. Result: From 2017 to 2019, there were 525 (1.1%) new AV patients out of a total of 45,754 new patients. AV was the major diagnosis in the Cosmetic Medic division. AV grades 2, 3, and 4 were found in 167 patients (32.0%). The most common lesion was papulopustular (75.4%) and the most common risk factor was hormonal (58.7%). All the patients received tretinoin, clindamycin gel 1.2%, and sunscreen for topical treatment. Doxycycline was the most common oral antibiotic used (98.2%) Conclusion: The most common AV grade in this study was mild AV. Oral antibiotics were given to moderate-to-severe AV patients in combination with topical treatment to prevent resistance.
A Retrospective Study of Demographic, Clinical, and Histopathological Profiles of Cutaneous Tumors Lunardi Bintanjoyo; Afif Nurul Hidayati; Dwi Murtiastutik; Muhammad Yulianto Listiawan
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 3 (2022): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.3.2022.149-155

Abstract

Background: In 2007, skin cancers were third most common malignancies in Indonesia. However, profile of cutaneous tumors in our institution has not been studied. Purpose: To evaluate profile of cutaneous tumors in Dermatology and Venerology Outpatient Clinic, Dr. Soetomo General Hospital, Surabaya, Indonesia. Methods: This is a descriptive retrospective study. Inclusion criteria was new cutaneous tumor patients. Exclusion criteria was incomplete data. Medical record and  photograph database from 2019-2020 were assessed for demography, clinical features, histopathological examination and final diagnosis. Results: There were 379 (5,5%) cutaneous tumors among 6896 new patients at Dermatology and Venereology Outpatient Clinic. Overall, there were more female patients (53.7%) and age group of 0-45 years old (70.4%). Cutaneous tumors more commonly presented as papular (50.4%), multiple (56.5%), nonpigmented (58.3%), asymptomatic lesions (62.5%), with time from onset 0-24 months (66.2%) and location on head and face (61.2%). Benign cutaneous tumors showed similar findings. Malignant cutaneous tumors showed differences including predominantly male sex, age above 45 years old, nodular, solitary, pigmented and easily bleeding lesions. Malignant tumors were less common (6.9%). Most common malignant tumor was BCC. Most common benign and overall cutaneous tumor was seborrheic keratosis. Conclusion: Cutaneous  tumors presented across gender and ages, showing heterogenous clinical manifestations. Malignant and benign cutaneous tumors showed similarity on time from onset and location of lesions. However, differences were seen in demographic profiles and majority of clinical features. BCC was the most common malignant cutaneous tumors, while seborrheic keratosis was the most common benign and overall cutaneous tumors.
Skin Prick Test Profile: A Retrospective Study Nopriyati Nopriyati; Cayadi Sidarta Antonius; H. M. Athuf Thaha; Sarah Diba; Yuli Kurniawati; Fifa Argentina
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 3 (2022): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.3.2022.189-196

Abstract

Background: A skin prick test is one method to detect allergies. Skin prick testing in dermatology can be performed on atopic dermatitis and urticaria. Skin prick test can be done easily, it’s relatively safe, fast, and can use many allergens simultaneously in one test. Purpose: To describe the characteristics of the skin prick test results at the clinic of Dermatology and Venereology, Mohammad Hoesin Palembang General Hospital, for the period 2016-2021. Methods: Descriptive retrospective study using a cross-sectional approach. Medical record data for the period January 2016-December 2021. Result: The number of patients who underwent skin prick testing during the period January 2016 to December 2021 was 116 patients, dominated by women (59.5%) and those aged 26-35 years (40.5%). The majority of diagnoses examined were atopic dermatitis (48.3%) and chronic urticaria (31.9%). The most positive results were for allergens in the form of house dust mites, shrimp, and crabs. The positive proportion of milkfish allergen was higher in women, while the positive proportion of shrimp allergen was higher in men. Chicken feather allergen showed significant differences between the diagnoses of atopic dermatitis, chronic urticaria and acute urticaria. Conclusion: House dust mites were the dominant allergen in patients with atopic dermatitis, chronic urticaria, and acute urticaria. skin prick test is recommended to be performed in the management of atopic dermatitis, chronic urticaria, and acute urticaria in order to detect the allergen because it has significant clinical relevance.
Susceptibility of Male who Have Sex with Male to High-Risk Type Human Papillomavirus (HPV) 16 and 18 with Condyloma Acuminata Prasetyadi Mawardi; Danu Yuliarto
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 3 (2022): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.3.2022.197-202

Abstract

Background: Condyloma acuminatum (CA) or genital warts are sexually transmitted infections caused by human papillomavirus (HPV). It is estimated that CA occurs in >80% of reproductive age in many countries, with the most common subtypes being 6 and 11. Purpose: The aim of the study to reveal the high risk (HR)-HPV in various condyloma acuminata in Dr. Moewardi Hospital. Methods: This study was a cross-sectional analytical observational study that assessed data collection concurrently over time. Specimens were patients diagnosed with condyloma acuminatum, biopsies were performed, and immunohistochemical staining was also performed. The sampling technique used sequential sampling, and the inclusion criteria included patients who came to our hospital for treatment. Results: The majority of the male sample was MSM. According to HIV status, 6 (30%) male patients were found to be positive. Immunohistochemistry showed that 15% of the samples were HR-HPV. Statistical test results for HR-HPV and low-risk (LR) HPV were significant, p-value = 0.038. Conclusion: Condyloma acuminatum is a sexually transmitted infection that usually occurs at the same time as HIV infection. In our study all patients with HR-HPV were MSM.

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